Importance

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Abstract

A radioisotope labeled reagent includes a compound having the general formula (I),

description='In-line Formulae' end='lead'L-(^aC^bH₂)_n^aC^5bH₃  (I)description='In-line Formulae' end='tail'

where a in each occurrence independently is a carbon mass number between 11 and 14 inclusive, b in each occurrence independently is a hydrogen mass number between 1 and 3 inclusive, such that a in each occurrence is not 12 simultaneously with b in each occurrence being 1; L is a leaving group R¹SO₂—O—, R¹—S—, ¹²C¹H₃(¹²C¹H₂)_n—S—R¹C(O)O—, NC—, (R¹)₃P—, XMg— and Li—, where n is an integer between 0 and 3 inclusive, where X is chloro, bromo or iodine, where R¹ is H, aryl, a substituent containing aryl, C₁-C₂₀ alkyl, a substituent containing C₁-C₂₀ alkyl, C₂-C₂₀ alkenyl, a substituent containing C₂-C₂₀ alkenyl, C₂-C₂₀ alkynyl, and a substitute containing C₂-C₂₀ alkynyl with the proviso that when n is 0, a is 13 and b is 2 and R¹ in R¹—S is not aryl.

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First Claim