Targeting of antigen presenting cells with immunonanotherapeutics

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 8343497
APP PUB NO 20100129392A1
SERIAL NO

12428381

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides nanocarriers capable of stimulating an immune response in T cells and/or in B cells. The invention provides nanocarriers that comprise an immunofeature surface. The nanocarriers are capable of targeting antigen presenting cells when administered to a subject. The invention provides pharmaceutical compositions comprising inventive nanocarriers. The present invention provides methods of designing, manufacturing, and using inventive nanocarriers and pharmaceutical compositions thereof.

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Patent Owner(s)

  • THE BRIGHAM AND WOMEN'S HOSPITAL, INC.;PRESIDENT AND FELLOWS OF HARVARD COLLEGE;MASSACHUSETTS INSTITUTE OF TECHNOLOGY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Alexis, Frank Greenville, US 28 1700
Basto, Pamela Somerville, US 21 1621
Farokhzad, Omid C Chestnut Hill, US 88 4041
Iannacone, Matteo Boston, US 24 1384
Langer, Robert S Newton, US 635 37250
Moseman, Elliott Ashley Jamaica Plain, US 17 866
Shi, Jinjun Boston, US 63 3061
Tonti, Elena Riccione, IT 12 634
von, Andrian Ulrich Chestnut Hill, US 18 925

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