Methods and systems for multi-antibody therapies

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United States of America Patent

PATENT NO 8349326
APP PUB NO 20110129474A1
SERIAL NO

12889511

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to methods and systems for administering antibody therapeutic agents. The methods include administering one or more (e.g., two or three) binding agents, wherein each of the binding agents has one or more monomers that have a binding region that is specific to a portion of a disease agent and one or more copies of a tag. The binding agents can be specific to one or more portions of the same or different disease agents. The tag is the same for each of the binding agents. The methods include administering an anti-tag antibody, wherein the anti-tag antibody has an anti-tag region that is specific to the tag, and can have an immunoglobulin (e.g., IgA, IgD, IgE, IgG, and IgM). Disease agents include bacteria, bacterial proteins, viruses, viral proteins, cancer cells, and proteins or toxins produced therefrom or from other sources such as snakes, insects, plants, etc. In particular, the present invention includes methods and systems for binding agents having one or more monomers that are specific to neurotoxins that cause botulism.

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Patent Owner(s)

Patent OwnerAddress
TRUSTEES OF TUFTS COLLEGEBALLOU HALL MEDFORD MA 02155

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Mukherjee, Jean Worcester, US 4 40
Shoemaker, Charles B North Grafton, US 25 312

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