Methods for stimulating an immune response using bacterial antigen delivery system
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United States of America Patent
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Jan 22, 2013
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Oct 3, 2006
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Oct 4, 2005
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Abstract
The invention relates to the use of the type III secretion system of bacteria to stimulate immune responses against tumor antigen(s) for treating antigen-loss variant tumors. Methods are provided for stimulating and/or increasing an immune response against tumor antigens. The invention also relates to the preparation of antigen presenting cells from peripheral blood mononuclear cells using bacteria having a type III secretion system.
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