Pharmacokinetically improved compounds

United States of America Patent

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Jan 22, 2013
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Mar 27, 2006
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Mar 25, 2005

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Abstract

The present invention relates to inhibitors of ROCK1 and ROCK2 and methods of modulating the pharmacokinetic and/or pharmacodynamic properties of such compounds. Also provided are methods of inhibiting ROCK1 and or ROCK2 that are useful for the treatment of disease.

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SURFACE LOGIX LLC	737 CONCORD AVENUE CAMBRIDGE MA 02138

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Inventor Name	Address	# of filed Patents	Total Citations
Bartolozzi, Alessandra	Somerville, US	31	762
Campbell, Stewart	Framingham, US	24	530
Foudoulakis, Hope	Framingham, US	9	88
Kirk, Brian	Sudbury, US	64	10262
Ram, Siya	Winchester, US	34	384
Sweetnam, Paul	Marblehead, US	27	490

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Pharmacokinetically improved compounds

Number of patents in Portfolio can not be more than 2000

United States of America Patent

11887218

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US Family Size	Non-US Coverage
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DATE PUBLISHED	PUBLICATION/PATENT NO.	PUBLICATION TYPE
January 22, 2013	US,8357693,B2 US8357693B2	GRANTED PATENT AS SECOND PUBLICATION
June 10, 2010	US,20100144707,A1 US20100144707A1	FIRST PUBLISHED PATENT APPLICATION

PATENT NO	8357693
SERIAL NO	11887218
DOCKET NO

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11887218

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