Phosphotriester-modified oligonucleotide primers for nucleic acid amplification
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United States of America Patent
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Jan 29, 2013
Grant Date -
Dec 6, 2007
app pub date -
May 17, 2007
filing date -
Jun 1, 2006
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Abstract
The present invention provides methods and compositions for nucleic acid amplification. These methods involve the use of oligonucleotide primers in temperature dependent nucleic acid amplification reactions. In certain aspects, the methods are accomplished by use of certain modified oligonucleotide primers which provide utility in nucleic acid amplification. In preferred embodiments, the oligonucleotide primers are modified with particular chemical groups such as esters.
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