Methods of treating cholesterol gallstone disease with ezetimibe
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United States of America Patent
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Jan 29, 2013
Grant Date -
Jan 21, 2010
app pub date -
Apr 4, 2006
filing date -
Apr 4, 2005
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Abstract
This invention discloses the use of compounds of the azetidinone family in treatment of cholesterol gallstone disease of the biliary tree in mammals. These drugs act by decreasing biliary cholesterol secretion, and at the same time increasing the biliary flow and the hepatic secretion of endogenous compounds (e.g. bile salts, phospholipids) into the bile, in turn, these endogenous compounds contribute to inhibiting precipitation and the formation of gallstones in the biliary tree.
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