Methods and compositions related to internalizing RGD peptides
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United States of America Patent
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Feb 5, 2013
Grant Date -
Oct 1, 2009
app pub date -
Jan 16, 2009
filing date -
Jan 18, 2008
priority date (Note) -
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Abstract
Disclosed are compositions and methods useful for targeting tissue undergoing angiogenesis or to cells or tissue expressing αv integrins. The compositions and methods are based on peptide sequences that selectively bind to and home to tissue undergoing angiogenesis or to cells or tissue expressing αv integrins in animals. The disclosed targeting is useful for delivering therapeutic and detectable agents to tissue experiencing angiogenesis or to cells or tissue expressing αv integrins.
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