Fc variants with altered binding to FcRn
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United States of America Patent
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Feb 5, 2013
Grant Date -
Jun 25, 2009
app pub date -
Dec 22, 2008
filing date -
Nov 12, 2004
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Abstract
The present application relates to a variant Fc region comprising at least one modification relative to a wild-type human Fc region, where the modification selected from the group consisting of 434S, 252Y/428L, 252Y/434S, and 428L/434S, and the numbering is according to the EU index.
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