Pharmaceutical use of substituted amides

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United States of America Patent

PATENT NO 8383683
APP PUB NO 20100087543A1
SERIAL NO

12597129

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The use of substituted amides for modulating the activity of 11β-hydroxysteroid dehydro-genase type 1 (11βHSD1) and the use of these compounds as pharmaceutical composi-tions, are described. Also a novel class of substituted amides, their use in therapy, phar-maceutical compositions comprising the compounds, as well as their use in the manufac-ture of medicaments are described. The present compounds are modulators and more specifically inhibitors of the activity of 11βHSD1 and may be useful in the treatment of a range of medical disorders where a decreased intracellular concentration of active gluco-corticoid is desirable.

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Patent Owner(s)

Patent OwnerAddress
VTVX HOLDINGS II LLC4170 MENDENHALL OAKS PKWY HIGH POINT NC 27265

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Andersen, Henrik Sune Lyngby, DK 89 1132
Ebdrup, Soren Roskilde, DK 44 232

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