Integration of micro and macro information for biomedical imaging
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United States of America Patent
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Feb 26, 2013
Grant Date -
Feb 17, 2011
app pub date -
Oct 23, 2009
filing date -
Oct 27, 2008
priority date (Note) -
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Abstract
Macroscopic imaging data, such as from a CT, MR, PET, or SPECT scanner, is obtained. Microscopic imaging data of at least a portion of the same tissue is obtained. To align the microscopic imaging data with the macroscopic imaging data, intermediate data is also obtained. For example, photographic data is acquired at an intermediary stage of a process of preparing tissue for microscopic scan. The macroscopic and microscopic data are registered to the intermediary photographic data. Once registered to the intermediary data, the spatial relationship between the macroscopic and microscopic data is known and may be used for imaging or quantification.
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