Devices and methods for inhibiting granulocyte activation by neural stimulation

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United States of America Patent

PATENT NO 8391970
APP PUB NO 20090062874A1
SERIAL NO

12198808

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Abstract

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Described herein are methods, devices and systems for inhibition of granulocyte activation by appropriate stimulation of the vagus nerve. Methods of treating granulocyte-mediated disorders (including inflammatory disorders) by stimulating the vagus nerve to inhibit granulocyte activation (particularly neutrophil activation) are also described. Appropriate stimulation may be very low levels of stimulation, including stimulation that does not result in desensitization. The level of granulocyte activation may be detected and used to at least partially control stimulation.

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Patent Owner(s)

  • THE FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Metz, Christine N Great Neck, US 13 147
Tracey, Kevin J Old Greenwich, US 119 3693
Warren, Howland Shaw Cambridge, US 8 320

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