Inhalable aztreonam lysinate formulation for treatment and prevention of pulmonary bacterial infections

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United States of America Patent

PATENT NO 8399496
APP PUB NO 20090028801A1
SERIAL NO

12229425

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Abstract

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A method and a composition for treatment of pulmonary bacterial infections caused by gram-negative bacteria suitable for treatment of infection caused by Escherichia coli, Klebsiella pneumoniae, Klebsiella oxytoca, Pseudomonas aeruginosa, Haemophilus influenzae, Proteus mirabilis, Enterobacter species, Serratia marcescens as well as those caused by Burkholderia cepacia, Stenotrophomonas maltophilia, Alcaligenes xylosoxidans, and multidrug resistant Pseudomonas aeruginosa, using a concentrated formulation of aztreonam lysinate delivered as an aerosol or dry powder formulation.

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Patent Owner(s)

Patent OwnerAddress
GILEAD SCIENCES INC333 LAKESIDE DRIVE FOSTER CITY CA 94404

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Keller, Manfred München, DE 63 1814
Lintz, Frank-Christophe Starnberg, DE 5 319
Montgomery, Alan Bruce Seattle, US 31 285

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