Antagonists of IL-6 to raise albumin and/or lower CRP
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United States of America Patent
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Mar 26, 2013
Grant Date -
Nov 26, 2009
app pub date -
Nov 25, 2008
filing date -
May 21, 2007
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Abstract
The present invention is directed to therapeutic methods using IL-6 antagonists such as antibodies and fragments thereof having binding specificity for IL-6 to improve survivability or quality of life of a patient in need thereof. In preferred embodiments these patients will comprise those exhibiting (or at risk of developing) an elevated serum C-reactive protein level or a reduced serum albumin level prior to treatment. In another preferred embodiment, the patient's Glasgow Prognostic Score will be increased and survivability will preferably be improved.
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