Cytotoxic agents comprising new tomaymycin derivatives and their therapeutic use
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United States of America Patent
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Mar 26, 2013
Grant Date -
Dec 16, 2010
app pub date -
Jan 19, 2010
filing date -
Jul 19, 2007
priority date (Note) -
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Abstract
The invention relates to novel tomaymicine derivatives comprising a linker. It also relates to the conjugate molecules that comprise one or more of said tomaymicine derivatives covalently linked to a cell binding agent through a linking group that is present on the linker of the tomaymycin derivative. It also relates to the preparation of the tomaymicine derivatives and of the conjugate molecules.
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