Xanthones, thioxanthones and acridinones as DNA-PK inhibitors

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United States of America Patent

PATENT NO 8404681
APP PUB NO 20070167441A1
SERIAL NO

10550978

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Compound that inhibit DNA-dependent protein kinase, compositions comprising the compounds, methods of inhibiting the DNA-PK biological activity, methods of sensitizing cells the agents that cause DNA lesions, and methods of potentiating cancer treatment are disclosed.

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Patent Owner(s)

Patent OwnerAddress
ICOS CORPORATIONC/O ELI LILLY & CO LILLY CORPORATE CENTER INDIANAPOLIS IN 46285

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Burgess, Laurence E Boulder, US 49 610
Eary, Charles T Longmont, US 3 78
Halbrook, James W Mercer Island, US 1 16
Kesicki, Edward A Bothell, US 73 2351
Schiro, Justin G Baudette, US 3 78
Schlachter, Stephen T Boulder, US 49 727

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