Manufacturing process of making polymeric amine salts
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United States of America Patent
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Mar 26, 2013
Grant Date -
Jun 3, 2010
app pub date -
Dec 2, 2009
filing date -
Dec 3, 2008
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Abstract
A novel process of manufacturing sevelamer carbonate from a polyallylamine carbonate or bicarbonate chloride salt. Process for manufacture of carbonate and/or bicarbonate salts of water insoluble polymers containing amino groups that are useful as anion binders in the gastrointestinal (GI) system. The process arranges the polyallylamine chain in a solution in such a way that the cross-linking reaction with epichlorohydrin can be controlled at a desired reaction rate.
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