Blood and cell analysis using an imaging flow cytometer
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United States of America Patent
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Mar 26, 2013
Grant Date -
Sep 16, 2010
app pub date -
Dec 4, 2009
filing date -
Jan 25, 1999
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Abstract
Multimodal or multispectral images of cells comprising a population of cells are simultaneously collected. Photometric and/or morphometric image features identifiable in the images are used to identify differences between first and second populations of cells. The differences can include changes in a relative percentage of different cell types in each population, or a change in a first type of cell present in the first population of cells and the same type of cell in the second population of cells. The changes may be indicative of a disease state, indicative of a relative effectiveness of a therapy, or indicative of a health of the person from whom the cells populations were obtained.
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