Detection and monitoring of liver damage

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United States of America Patent

PATENT NO 8409878
APP PUB NO 20110244490A1
SERIAL NO

12979715

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Abstract

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A method of detecting liver damage in a subject comprises measuring the level of caspase-3 generated cytokeratin-18 fragments in the bodily sample. The level of measuring the level of caspase-3 generated cytokeratin-18 fragments is then correlated with liver disease progression.

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Patent Owner(s)

Patent OwnerAddress
THE CLEVELAND CLINIC FOUNDATION9500 EUCLID AVENUE MAIL CODE GCIC-10 CLEVELAND OH 44195 44195

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Feldstein, Ariel E Highland Heights, US 5 26
Wieckowska, Anna Quebec, CA 4 12
Zein, Nizar Highland Heights, US 7 14

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