Pyridazines
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United States of America Patent
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Apr 2, 2013
Grant Date -
Nov 11, 2010
app pub date -
Apr 28, 2010
filing date -
May 5, 2009
priority date (Note) -
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Abstract
The present invention is concerned with isoxazole-pyridazines of formula I, having affinity and selectivity for GABA A α5 receptor, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful as cognitive enhancer or for the therapeutic and/or prophylactic treatment of cognitive disorders like Alzheimer's disease.
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