Trypsin-like serine protease inhibitors, and their preparation and use

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United States of America Patent

PATENT NO 8410310
APP PUB NO 20120225913A1
SERIAL NO

13471007

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Abstract

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The invention relates to inhibitors of trypsin-like serine proteases of the general formula (I) which, as well as plasmin, also inhibit plasma kallikrein, and to their preparation and use as medicaments, preferably for treatment of blood loss, especially in the case of hyperfibrinolytic states, in organ transplants or heart surgery interventions, in particular with a cardiopulmonary bypass, or as a constituent of a fibrin adhesive.

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Patent Owner(s)

Patent OwnerAddress
QUALCOMM INCORPORATED5775 MOREHOUSE DRIVE SAN DIEGO CA 92121-1714

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Daghish, Mohammed Leipzig, DE 8 31
Heinicke, Jochen Leipzig, DE 8 53
Ludwig, Friedrich-Alexander Leipzig, DE 7 36
Nicklisch, Silke Leipzig, DE 3 30
Reichelt, Claudia Leipzig, DE 9 59
Schulze, Alexander Grosstreben, DE 13 98
Schweinitz, Andrea Jena, DE 18 142
Soeffing, Anett Weimar, DE 3 24
Steinmetzer, Peter Jena, DE 3 30
Steinmetzer, Torsten Jena, DE 20 504
Stuerzebecher, Joerg Erfurt, DE 9 69
Van, De Locht Andreas Munich, DE 4 30

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