Multifaceted endovascular stent coating for preventing restenosis
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United States of America Patent
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Apr 9, 2013
Grant Date -
Jul 21, 2005
app pub date -
Apr 23, 2003
filing date -
Apr 24, 2002
priority date (Note) -
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Abstract
This invention deals with a carboxyl-bearing, amphiphilic, solid copolyester stent coating composition for multifaceted prevention of vascular restenosis through a plurality of physicopharmacological modes. The composition includes one or more bioactive compounds and a copolymerization product of polyalkylene glycol, end-grafted with one or more cyclic monomer and treated further to introduce carboxyl-bearing end- or side-groups. The invention also deals with bioactive agents in an ionically conjugated form. The present coating may be applied to a metallic or an absorbable polymeric stent for use in preventing vascular restenosis.
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