Method for increasing expression yield of a protein of interest
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United States of America Patent
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Apr 9, 2013
Grant Date -
Jan 6, 2011
app pub date -
Feb 20, 2009
filing date -
Feb 25, 2008
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Abstract
The present invention relates to a method of producing a protein of interest comprising: (a) cultivating a mutant cell under conditions conducive for production of the protein wherein the mutant has a reduced or no expression of an endogenous polypeptide shown in SEQ ID NO: 2 compared to a parent host cell grown under the same conditions; and optionally (b) recovering the protein of interest.
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