1′-substituted-carba-nucleoside prodrugs for antiviral treatment

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Apr 9, 2013
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Jan 26, 2012
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May 26, 2011
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May 28, 2010

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Abstract

Provided are prodrugs of pyrrolo[1,2-f][1,2,4]triazin-7-yl nucleoside phosphates wherein the 1′ position of the nucleoside sugar is substituted with CN. The compounds, compositions, and methods provided are useful for the treatment Hepatitis C infections.

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GILEAD SCIENCES INC	333 LAKESIDE DRIVE FOSTER CITY CA 94404

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Inventor Name	Address	# of filed Patents	Total Citations
Cho, Aesop	Mountain View, US	78	3090
Kim, Choung U	San Carlos, US	138	4246
Ray, Adrian S	Redwood City, US	63	2372
Zhang, Lijun	Los Altos Hills, US	174	2085

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1′-substituted-carba-nucleoside prodrugs for antiviral treatment

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United States of America Patent

13117060

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PATENT NO	8415308
APP PUB NO	20120020921A1
SERIAL NO	13117060
DOCKET NO

US Family Size	Non-US Coverage
Patent Longevity	Forward Citations

DATE PUBLISHED	PUBLICATION/PATENT NO.	PUBLICATION TYPE
April 09, 2013	US,8415308,B2 US8415308B2	GRANTED PATENT AS SECOND PUBLICATION
January 26, 2012	US,20120020921,A1 US20120020921A1	FIRST PUBLISHED PATENT APPLICATION

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13117060

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