Pyridines

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United States of America Patent

PATENT NO 8415379
APP PUB NO 20100286132A1
SERIAL NO

12768762

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention is concerned with isoxazole-pyridines of formula I, having affinity and selectivity for GABA A α5 receptor, their manufacture, pharmaceutical compositions containing them and their use as pharmaceuticals. The active compounds of the present invention are useful as cognitive enhancer or for the therapeutic and/or prophylactic treatment of cognitive disorders like Alzheimer's disease.

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Patent Owner(s)

Patent OwnerAddress
ROCHE PALO ALTO LLC1 DNA WAY SOUTH SAN FRANCISCO CA 94080

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Jakob-Roetne, Roland Inzlingen, DE 77 404
Lucas, Matthew C Verona, US 62 562
Thomas, Andrew Binningen, CH 130 1431

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