Fibronectin based scaffold domain proteins that bind to PCSK9
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United States of America Patent
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Apr 16, 2013
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app pub date -
Apr 13, 2011
filing date -
Apr 13, 2010
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Abstract
The present invention relates to fibronectin based scaffold domain proteins that bind PCSK9. The invention also relates to the use of the innovative proteins in therapeutic applications to treat atherosclerosis, hypercholesterolemia and other cholesterol related diseases. The invention further relates to cells comprising such proteins, polynucleotides encoding such proteins or fragments thereof, and to vectors comprising the polynucleotides encoding the innovative protein.
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