Combined gene therapy for the treatment of macroscopic gliomas
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United States of America Patent
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Apr 16, 2013
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Aug 12, 2005
filing date -
Aug 12, 2004
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Abstract
Described herein are compositions and methods for the treatment of cancer, and particularly brain cancer (e.g., glioma) in a mammal. In various embodiments of the invention, a combined therapeutic approach including TK with systemic ganciclovir administration and Flt3L are used in connection with gene therapeutic techniques or direct peptide injection for the aforementioned indications. Kits useful in practicing the inventive method are also disclosed, as are animal models useful for studying brain cancer.
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