Methods for rapid multiplexed amplification of target nucleic acids

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United States of America Patent

PATENT NO 8425861
SERIAL NO

12080746

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Abstract

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A fast, multiplexed PCR system is described that can rapidly generate amplified nucleic acid products, for example, a full STR profile, from a target nucleic acid. Such systems include, for example, microfluidic biochips and a custom built thermal cycler, which are also described. The resulting STR profiles can satisfy forensic guidelines for signal strength, inter-loci peak height balance, heterozygous peak height ratio, incomplete non-template nucleotide addition, and stutter.

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Patent Owner(s)

  • ANDE CORPORATION

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Giese, Heidi Susanne Newburyport, US 10 79
Kellogg, Gregory John Cambridge, US 15 317
Lam, Heung Chuan Newton, US 17 372
Selden, Richard F Lincoln, US 82 1633
Tan, Eugene Arlington, US 44 649
Wright, John A Billerica, US 59 2000

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