Process for the preparation of recombinant polypeptides

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United States of America Patent

PATENT NO 8426168
APP PUB NO 20060269990A1
SERIAL NO

10568329

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to the preparation of a recombinant polypeptide, which polypeptide upon expression has been secreted into the periplasm of a transformed host cell. In particular, this invention relates to a process to enhance the extraction yield of the recombinant polypeptide from the periplasm before further downstream processing.

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Patent Owner(s)

  • NOVARTIS AG;SANDOZ AG

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Palma, Norbert Breitenbach a. Inn, AT 6 14
Stempfer, Günter Kufstein, AT 1 7

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