Method of drug design
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United States of America Patent
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Apr 23, 2013
Grant Date -
Jun 25, 2009
app pub date -
Oct 3, 2006
filing date -
Oct 4, 2005
priority date (Note) -
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Abstract
The invention provides a method of identifying biologically active compounds comprising: (a) designing a first library of compounds of formula (1) to scan molecular diversity wherein each compound of the library has at least two pharmacophoric groups R1 to R5 as defined below and wherein compound of the library has same number of pharmacophoric groups; (b) assaying the first library of compounds in one or more biological assay(s); and (c) designing a second library wherein each compound of the second library contains one or more additional pharmacophoric group with respect to the first library; such that the/each component of the first and second library is a compound of formula (1).
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