Diagnosis of mood disorders by detecting latent infection with human herpesvirus-6
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United States of America Patent
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Apr 30, 2013
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app pub date -
Sep 25, 2008
filing date -
Sep 27, 2007
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Abstract
Disclosed are a protein and a gene each of which is a factor involved in latent infection with a herpesvirus. An antibody against the factor was detected in approximately 50% of patients suffering from mental disorders, whereas the antibody was hardly detected in healthy persons. Further, a mouse having SITH-1 introduced therein developed a mental disorder such as a manic-depressive illness or depression-like disorder. Based on these findings, it is possible to provide a method for objectively determining a mental disorder and an animal model of a mental disorder.
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