Nucleic acids encoding polypeptide inhibitors of human plasmin derived from the Kunitz domains

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United States of America Patent

PATENT NO 8431359
APP PUB NO 20050186649A1
SERIAL NO

11083742

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Abstract

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This invention features novel proteins that are homologous to the first Kunitz domain (K1) of lipoprotein-associated coagulation inhibitor (LACI), and are capable of inhibiting plasmin and nucleic acids encoding these proteins. The invention also features the use of such proteins in therapeutic, diagnostic, and clinical methods.

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Patent Owner(s)

Patent OwnerAddress
DYAX CORP55 NETWORK DRIVE BURLINGTON MA 01803-2756

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ladner, Robert C Ijamsville, US 96 10745
Markland, William Southborough, US 38 5584

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