Natriuretic peptide-mediated imaging of atherosclerotic plaque
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United States of America Patent
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May 7, 2013
Grant Date -
Jan 28, 2010
app pub date -
May 22, 2009
filing date -
Jun 2, 2008
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Abstract
Tracers comprising an oligopeptide comprising a fragment of a natriuretic peptide, wherein the fragment comprises the sequence Arg-Ile-Asp-Arg-Ile (SEQ ID NO.: 1), and a signaling moiety, are disclosed. Further disclosed are methods of imaging atherosclerotic plaque by PET scanning or MRI using a tracer.
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