Gene detection assay for improving the likelihood of an effective response to a HER2 antibody cancer therapy
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United States of America Patent
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May 14, 2013
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Dec 12, 2011
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May 19, 2000
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Abstract
The invention provides a method for more effective treatment of patients susceptible to or diagnosed with tumors overexpressing HER2, as determined by a gene amplification assay, with a HER2 antibody. Such method comprises administering a cancer-treating dose of the HER2 antibody, preferably in addition to chemotherapeutic agents, to a subject in whose tumor cells her2 has been found to be amplified e.g., by fluorescent in situ hybridization.
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