G protein coupled receptor agonists and antagonists and methods of use
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United States of America Patent
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May 14, 2013
Grant Date -
Sep 4, 2008
app pub date -
Nov 4, 2005
filing date -
Nov 4, 2004
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Abstract
The invention relates generally to G protein coupled receptors (GPCRs) and in particular to GPCR agonists and antagonists, use of these compounds and their pharmaceutical compositions, e.g., in the treatment, modulation and/or prevention of physiological conditions associated with GPCRs, such as in treating conditions in which chemokine receptors play a role, e.g., sepsis, arthritis, inflammation and autoimmune diseases.
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