Assay method for Alzheimer's disease

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United States of America Patent

PATENT NO 8444977
APP PUB NO 20100279433A1
SERIAL NO

12834271

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Abstract

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A diagnostic test for preclinical and clinical Alzheimer's disease is based on plasma levels of Aβ40, Aβ42, their ratio, or their rate of entry following administration of antibodies that sequester Aβ. Alterations of any of these parameters from control values identifies preclinical or clinical Alzheimer's disease.

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Patent Owner(s)

  • ELI LILLY AND COMPANY;WASHINGTON UNIVERSITY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bales, Kelly R Coatsville, US 9 278
Cummins, David J Indianapolis, US 3 75
DeMattos, Ronald Noblesville, US 7 274
Holtzman, David M St. Louis, US 11 302
Paul, Steven M Carmel, US 18 335

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