Microfabricated crossflow devices and methods

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 8445210
SERIAL NO

12969411

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

A microfluidic device for analyzing and/or sorting biological materials (e.g., molecules such as polynucleotides and polypeptides, including proteins and enzymes; viruses and cells) and methods for its use are provided. The device and methods of the invention are useful for sorting particles, e.g. virions. The invention is also useful for high throughput screening, e.g. combinatorial screening. The microfluidic device comprises a main channel and an inlet region in communication with the main channel at a droplet extrusion region. Droplets of solution containing the biological material are deposited into the main channel through the droplet extrusion region. A fluid different from and incompatible with the solution containing the biological material flows through the main channel so that the droplets containing the biological material do not diffuse or mix. Biological material within the droplets can be analyzed and/or sorted by detecting a predetermined characteristic of the biological sample in each droplet and sorting the droplet accordingly.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

  • CALIFORNIA INSTITUTE OF TECHNOLOGY

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Quake, Stephen R Stanford, US 282 18548
Thorsen, Todd Pasadena, US 17 2111

Cited Art Landscape

Load Citation

Patent Citation Ranking

Forward Cite Landscape

Load Citation