Preparation of dihydropyridines
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United States of America Patent
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Jun 4, 2013
Grant Date -
Nov 10, 2011
app pub date -
May 6, 2011
filing date -
May 7, 2010
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Abstract
The invention relates to a method and compounds for the preparation of clevidipine butyrate, a very short acting hypertensive calcium antagonist, as well as the synthesis of these compounds useful for the preparation of clevidipine (also known as clevidipine butyrate). Moreover the invention also discloses polymorphic forms of clevidipine butyrate, useful for the preparation of pharmaceutical compositions, and processes to prepare them.
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