Superoxide dismutase variants and methods of use thereof
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United States of America Patent
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Jun 11, 2013
Grant Date -
May 17, 2012
app pub date -
Sep 20, 2011
filing date -
Sep 21, 2010
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Abstract
The present disclosure provides variant superoxide dismutase polypeptides, compositions comprising the polypeptides, and nucleic acids comprising nucleotide sequences encoding the polypeptides. The present disclosure provides methods of reducing oxidative damage in a cell, tissue, or organ. The present disclosure provides methods of identifying agents that increase superoxide dismutase activity.
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