Methods of using antibodies that bind the glutamate ligand binding region of Notch1
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United States of America Patent
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Jun 11, 2013
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app pub date -
Nov 30, 2011
filing date -
Jan 24, 2007
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Abstract
Isolated antibodies that specifically binds to an extracellular conserved ligand binding region of a human Notch receptor and inhibits growth of a tumor are described. Also described are methods of treating cancer, the method comprising administering an anti-Notch antibody in an amount effective to inhibit tumor growth.
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