Methods for identifying compounds that modulate untranslated region-dependent gene expression and methods of using same
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United States of America Patent
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Jun 11, 2013
Grant Date -
May 17, 2007
app pub date -
Jan 21, 2004
filing date -
Jan 21, 2003
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Abstract
The present invention relates to methods for identifying compounds that modulate untranslated region-dependent expression of a target gene. The invention particularly relates to using untranslated regions of a target gene or fragments thereof linked to a reporter gene to identify compounds that modulate untranslated region-dependent expression of a target gene. The methods of the present invention provide a simple, sensitive assay for high-throughput screening of libraries of compounds to identify pharmaceutical leads.
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