Targeting PAX2 for the treatment of breast cancer

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United States of America Patent

PATENT NO 8461101
APP PUB NO 20110223162A1
SERIAL NO

13114824

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Abstract

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The present application provides methods of prevention and/or treatment of breast cancer in a subject by inhibiting expression of PAX2. In the cancer treatment methods disclosed, the method of inhibiting expression of PAX2 can be by administration of a nucleic acid encoding an siRNA for PAX2. A method of treating cancer in a subject by administering DEFB1 is also provided. Similarly, provided is a method of treating cancer in a subject by increasing expression of DEFB1 in the subject.

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Patent Owner(s)

  • MEDICAL UNIVERSITY OF SOUTH CAROLINA;PHIGENIX, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Donald, Carlton D Mount Pleasant, US 32 35

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