1-pyrazolo[4,3-c]isoquinoline derivatives, preparation thereof and therapeutic use thereof

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United States of America Patent

PATENT NO 8461175
APP PUB NO 20120115898A1
SERIAL NO

13265981

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention relates to a compound of formula (I), where: R1 is a phenyl group optionally substituted by one or more halogen atoms; R2 is: a hydrogen atom or a halogen atom or a cyano group; a —C(═O)Y group where Y is a hydrogen atom, or a —NH2 or —OR3 group; a —C(═S)NH2 group; a —C(═NH)NH—OH group; a —CH2OH or —CH2F group; a —CH═N—OH group; a —CH═CH2 or —C═C—R3 group; a H or H R1 group being a hydrogen or (C1-C4)alkyl group; R3 is a hydrogen atom or (C1-C4)alkyl group; and R4 is a —NH2, (C1-C4)alkyl, (C1-C4)fluoroalkyl or (C3-C7)cycloalkyl group.

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Patent Owner(s)

Patent OwnerAddress
SANOFI AVENTIS174 AVENUE DE FRANCE F-75013 PARIS

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Delettre, Georges Paris, FR 1 0
Deprets, Stéphanie Paris, FR 3 2
Halley, Frank Paris, FR 43 406
Schio, Laurent Paris, FR 34 83
Thompson, Fabienne Paris, FR 29 211

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