Drug delivery from stents

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 8465758
APP PUB NO 20100275431A1
SERIAL NO

12773677

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A method of producing an intravascular stent has a coat comprising a crosslinked amphiphilic polymer and a sparingly water soluble matrix metalloproteinase inhibitor (MMPI). Preferably the polymer is formed from 2-methacryloyloxy-2′-ethyltrimethylammonium phosphate inner salt, C4-18 alkyl methacrylate and reactive and/or crosslinking monomer and the MMPI is a hydroxamic acid, more preferably batimastat. Preclinical and clinical results are reported, showing good luminal areas and reduced intimal thickening.

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Patent Owner(s)

  • ABBOTT LABORATORIES

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Driver, Michael J Surrey, GB 13 198
Lewis, Andrew L Surrey, GB 9 361
Stratford, Peter W Surrey, GB 12 470

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