Processes and compositions for methylation-based acid enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses

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United States of America Patent

PATENT NO 8476013
APP PUB NO 20100105049A1
SERIAL NO

12561241

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Abstract

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Provided are compositions and processes that utilize genomic regions differentially methylated between a mother and her fetus to separate, isolate or enrich fetal nucleic acid from a maternal sample. The compositions and processes described herein are useful for non-invasive prenatal diagnostics, including the detection of chromosomal aneuplodies.

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Patent Owner(s)

  • SEQUENOM, INC.;SEQUENOM CENTER FOR MOLECULAR MEDICINE

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ehrich, Mathias San Diego, US 66 1547
Nygren, Anders Olof Herman San Diego, US 17 306

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