Methods of treating neurological diseases by regulating migration of neuroblasts in the adult nervous system with tenascin-R

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United States of America Patent

PATENT NO 8481486
APP PUB NO 20090136565A1
SERIAL NO

12232307

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Abstract

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This invention provides a method for regulating migration of neuronal progenitor cells in the nervous system of a mammal. The method comprises providing a mammal with TNR, a biologically active fragment of TNR, or a TNR agonist in an amount sufficient to direct migration of the neuronal progenitor cells. The invention provides a method of treating neurological diseases by replenishing diseased, damaged, or destroyed neural cells in the central nervous system or in the peripheral nervous system.

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INSTITUT PASTEUR75724 PARIS CEDEX 15

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
de, Chevigny Antoine Paris, FR 2 1
Lledo, Pierre-Marie Antony, FR 6 6
Saghatelyan, Armen Gif-sur-Yvette, FR 3 17

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