Method for designing an aptamer

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United States of America Patent

PATENT NO 8484010
APP PUB NO 20120123760A1
SERIAL NO

13298830

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Disclosed in this specification is a method for identifying at least one aptamer that can bind to a bio-molecular target. The aptamer is designed in silico based on the structure of the target molecule. The process includes the steps of determining a first seed residue and growing an oligomer, one residue at a time, while maximizing the entropy of target-oligomer complex or minimizing the binding energy after the addition of each oligomer.

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Patent Owner(s)

Patent OwnerAddress
TECHNOLOGY INNOVATIONS LLC150 LUCIUS GORDON DRIVE WEST HENRIETTA NY 14586

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Tseng, Chih-Yuan Edmonton, CA 20 70
Tuszynski, Jack A Edmonton, CA 13 688

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