Itraconazole compositions with improved bioavailability

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United States of America Patent

PATENT NO 8486456
APP PUB NO 20090214656A1
SERIAL NO

11997256

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Abstract

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A solid dispersion product comprising itraconazole and hydroxypropyl methylcellulose, which satisfies the Formula 0.35>ΔHtr (1) (wherein ΔHtr represents the endotherm (J/g) accompanying a transition at about 240° C). The solid dispersion product shows an improved bioavailability.

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Patent Owner(s)

Patent OwnerAddress
STIEFEL LABORATORIES INC2711 CENTERVILLE ROAD SUITE 400 WILMINGTON NEW CASTLE DE 19808

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Berndl, Gunther Herheim am Berg, DE 41 448
Degenhardt, Matthias Limburgerhof, DE 18 147
Dispersyn, Gerrit Pennington, US 3 45
Mäegerlein, Markus Mannheim, DE 2 7

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