Systems and methods for membraneless dialysis

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United States of America Patent

PATENT NO 8491516
APP PUB NO 20120061304A1
SERIAL NO

13298344

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Abstract

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Devices, systems and methods are disclosed for removing undesirable materials from a sample fluid by contact with a second fluid. The sample fluid flows as a thin layer adjacent to, or between, concurrently flowing layers of the second fluid, without an intervening membrane. In various embodiments, a secondary separator is used to restrict the removal of desirable substances and effect the removal of undesirable substances from blood. The embodiments may be used for the removal of components from a sample fluid that vary in size. When blood is the sample fluid, for example, this may include the removal of small molecules, middle molecules, macromolecules, macromolecular aggregates, and cells, from the blood sample to the extractor fluid.

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Patent Owner(s)

  • THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Leonard, Edward F Bronxville, US 29 506
Shapley, Nina C New York, US 7 210
Tang, Zhongliang San Diego, US 21 842
West, Alan C Tenafly, US 27 557

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