Viruses for the treatment of cellular proliferative disorders

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United States of America Patent

PATENT NO 8491886
SERIAL NO

13297384

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Abstract

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Methods for treating cell proliferative disorders by administering virus to proliferating cells having an activated Ras-pathway are disclosed. The virus is administered so that it ultimately directly contacts proliferating cells having an activated Ras-pathway. Proliferative disorders include but are not limited to neoplasms. The virus is selected from modified adenovirus, modified HSV, modified vaccinia virus and modified parapoxvirus orf virus. Also disclosed are methods for treating cell proliferative disorders by further administering an immunosuppressive agent.

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Patent Owner(s)

  • ONCOLYTICS BIOTECH INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Coffey, Matthew C Calgary, CA 88 791
Thompson, Bradley G Calgary, CA 78 716

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